Drug Hypersensitivity Meeting – DHM5 2012

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Topics

• Epidemiology of hypersensitivity drug reactions
• Pharmacovigilance and prediction
• Pharmacogenetics (genetic tests to prevent allergic reactions to drugs)
• Risk factors for drug hypersensitivity (e.g. HLA associations)
• Relevant immunological background to drug hypersensitivity
• Fundamental mechanistical principles of drug hypersensitivity
• Drug hypersensitivity and viral disease: the dynamic interaction
• Contact allergy meets drug hypersensitivity
• Animal models to understand drug hypersensitivity in man
• Progression of cell injury to inflammation and hypersensitivity
• Cross reactivity in drug hypersensitivity
• Latest research on drug hypersensitivity in abstracts and presentations
• Severe cutaneous and systemic reactions (e.g. TEN, SJS, DRESS)
• Drug anaphylaxis
• Internal organ involvement in drug hypersensitivity
• Construction of a test plan in drug hypersensitivity
• In vivo diagnostic tests (skin tests, provocation tests)
• In vitro diagnostic tests (serum specific IgE assays, basophil activation test, lymphocyte activation test, ELIspot)
• Diagnosis and clinical management of hypersensitivity reactions to: antibiotics (betalactam and non-betalactam), nonsteroidal anti-inflammatory drugs, antineoplastic agents, contrast media, muscle relaxants and other perioperative drugs, biological agents, anticonvulsants, anticoagulants, new drugs, vaccines
• Treatment of hypersensitivity drug reactions
• Desensitisation or tolerance induction in drug hypersensitivity (protocols for antibiotics, antineoplastic agents, biological agents etc.)

Target audience

• Specialists in the fields of immunology, immunopathology, toxicology, genetic, pharmacology, pharmacogenetic, epidemiology and clinical research
• Pharmaceutical companies
• Regulatory agencies

Organising Committee

K. Brockow, DHM5 Chair
D. Naisbitt, DHM5 Co-Chair
W. Pichler, Past DHM Chair
B.K. Park, Past DHM Chair
J.C. Roujeau, Past DHM Chair
P. Demoly, Past DHM Chair
A. Romano, Past DHM Chair
A. Bircher
M. Blanca
M. Castells
A. Cavani
Y.T. Chen
H.P. Hoffmann
M. Kammüller
T. Kawabata
S.H. Kim
S. Mallal
S.F. Martin
H. Merk
M. Mockenhaupt
J.F. Nicolas
R. Pieters
M. Pirmohamed
J. Ring
N. Shear
T. Shiohara
A. Trautmann
J. Uetrecht
C. Yu